Article
Amino Acid at Position 166 of NS2A in Japanese Encephalitis Virus (JEV) is Associated with In Vitro Growth Characteristics of JEV.
Viruses - 30 Jun 2020
Tajima Shigeru, Taniguchi Satoshi, Nakayama Eri, Maeki Takahiro, Inagaki Takuya, Lim Chang-Kweng, Saijo Masayuki
Abstract excerpt
We previously showed that the growth ability of the Japanese encephalitis virus (JEV) genotype V (GV) strain Muar is clearly lower than that of the genotype I (GI) JEV strain Mie/41/2002 in murine neuroblastoma cells. Here, we sought to identify the region in GV JEV that is involved in its low growth potential in cultured cells. An intertypic virus containing the NS1-3 region of Muar in the Mie/41/2002 backbone...
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