Article
Mutations in the envelope protein of Japanese encephalitis virus affect entry into cultured cells and virulence in mice.
Virology - 1 Nov 1992
Hasegawa H, Yoshida M, Shiosaka T, Fujita S, Kobayashi Y
Abstract excerpt
The nucleotide sequences of the envelope protein of the Kamiyama 1 strain of Japanese encephalitis (JE) virus and a passaged mutant (Kamiyama 2 strain) were determined. Two amino acid differences, Ser-Phe at residue 364 and Asn-Ile at residue 367, distinguished Kamiyama 2 from Kamiyama 1. Six neu...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Cells, Cultured
- Encephalitis Virus, Japanese
- Encephalitis, Japanese
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Mutation
- Neutralization Tests