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Article

Role of FOXO Transcription Factors in Cancer Metabolism and Angiogenesis

30 Jun 2020

Abstract excerpt

Forkhead box O transcription factors (FOXOs) regulate several signaling pathways and play crucial roles in health and disease. FOXOs are key regulators of the expression of genes involved in multiple cellular processes and their deregulation has been implicated in cancer. FOXOs are generally considered tumor suppressors and evidence also suggests that they may have a role in the regulation of cancer metabolism...

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PMID: 32629884
DOI: 10.3390/cells9071586

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