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Article

The impact of BDNF Val66Met on cognitive skills in veterans with posttraumatic stress disorder.

Neuroscience letters - 14 Sept 2020

Havelka Mestrovic Ana, Tudor Lucija, Nedic Erjavec Gordana, Nikolac Perkovic Matea, Svob Strac Dubravka, Kovacic Petrovic Zrnka, Pivac Nela

Abstract excerpt

Posttraumatic stress disorder (PTSD) is a trauma-induced disorder characterized with impaired cognitive function. BDNF modulates cognition and is involved in neuroprotection and neurocognitive processing. The BDNF Val66Met polymorphism was found to influence cognitive functions. In PTSD, carriers of the BDNF GG genotype had better spatial processing of navigation performance, and lower hyperarousal and startle...

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Brain-Derived Neurotrophic Factor
Cognition
Executive Function
Memory, Short-Term
Methionine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stress Disorders, Post-Traumatic

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PMID: 32629065
DOI: 10.1016/j.neulet.2020.135235

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