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Article

Depression and Cognitive Dysfunction in Older U.S. Military Veterans: Moderating Effects of BDNF Val66Met Polymorphism and Physical Exercise.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Sept 2020

Pitts Barbara L, Wen Vivian, Whealin Julia M, Fogle Brienna M, Southwick Steven M, Esterlis Irina, Pietrzak Robert H

Abstract excerpt

OBJECTIVE: Depression is associated with increased risk for cognitive dysfunction, yet little is known about genetic and behavioral factors that may moderate this association. Using data from a nationally representative sample of older U.S. military veterans, we examined the direct and interactive effects of depression, brain-derived neurotropic factor (BDNF) Val66Met genotype, and physical exercise on cognitive...

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Brain-Derived Neurotrophic Factor
Cognition
Cognitive Dysfunction
Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Military Personnel

Outcome Assessment, Health Care

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PMID: 32122804
DOI: 10.1016/j.jagp.2020.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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