Article
The K469E polymorphism of the intercellular adhesion molecule-1 gene is associated with plasma fibrinogen level in type 2 diabetes.
Metabolism: clinical and experimental - 1 Mar 2005
Yokoyama Hisayo, Tahara Hideki, Emoto Masanori, Fujiwara Shigehiko, Araki Takahiro, Shinohara Kayo, Hatsuda Sawako, Maeno Takaaki, Shoji Takuhito, Koyama Hidenori, Shoji Tetsuo, Nishizawa Yoshiki
Abstract excerpt
Intercellular adhesion molecule-1 (ICAM-1) is involved in inflammation and development of atherosclerotic change of vascular endothelium. The aim of the present study is to investigate whether K469E polymorphism of the ICAM-1 gene is associated with various clinical factors including plasma fibrinogen in patients with type 2 diabetes. ICAM-1 gene polymorphism was examined using polymerase chain reaction and...
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