Article
Role of non-HLA genetic variants in end-stage renal disease.
Tissue antigens - 1 Aug 2009
Ranganath P, Tripathi G, Sharma R K, Sankhwar S N, Agrawal S
Abstract excerpt
Cytokines and intercellular adhesion molecule (ICAM) play a crucial role in the pathogenesis of primary kidney disease and progression to end-stage renal disease (ESRD). Cytokine secretion is reported to be dependent on the single nucleotide polymorphisms located in the cytokine genes. The role of different polymorphisms in cytokines and ICAM genes as probable susceptibility factors for ESRD has been explored in...
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