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Article

Association of TRDMT1 Gene Polymorphisms With Neuroblastoma Susceptibility: Insights From a Case-Control Study.

Journal of cellular and molecular medicine - 1 Sept 2025

Zhang Mengzhen, Zhang Wenli, Zhou Chunlei, Chang Jiaming, Liu Jiabin, Lin Lei, Zhang Xinxin, Chen Liping, He Jing, Han Baowei

Abstract excerpt

Neuroblastoma is the most common extracranial solid tumour in children, and genetic susceptibility plays a crucial role in its development. The impact of tRNA Dimethyltransferase 1 (TRDMT1), a primary methyltransferase catalysing 5-methylcytosine (m5C) RNA modification, on neuroblastoma susceptibility remains unexplored. We conducted a case-control study involving 402 neuroblastoma patients and 473 controls from...

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Identifiers

PMID: 40984038
DOI: 10.1111/jcmm.70848
PMCID: PMC12454185

Genes

TRDMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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