Article
Association of MALAT1 gene polymorphisms with neuroblastoma susceptibility in children from Jiangsu Province.
Human genomics - 12 Dec 2025
Lian Yong, He Lili, Dong Siqi, Li Mengjia, Zhang Wenli, Zhang Mengzhen, Zhang Xinxin, Zhou Chunlei, He Jing
Abstract excerpt
BACKGROUND: Neuroblastoma, a clinically heterogeneous pediatric tumor, has varying outcomes ranging from spontaneous regression to aggressive metastasis. Recent studies have emphasized non-coding RNAs, particularly long non-coding RNAs (lncRNAs), as crucial regulators of cancer epigenetics. MALAT1 is a dual oncogenic lncRNA with some therapeutic potential but has rarely been studied in neuroblastoma. METHODS: We...
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