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Telomere Length Measurement by Molecular Combing

16 Jun 2020

Abstract excerpt

Telomeres are repetitive regions of DNA bound by specialized proteins at the termini of linear chromosomes that prevent the natural chromosome ends from being recognized as DNA double strand breaks. Telomeric DNA is gradually eroded with each round of cell division, resulting in the accumulation of critically short or dysfunctional telomeres that eventually trigger cellular senescence. Consequently, telomere...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 32612998
DOI: 10.3389/fcell.2020.00493

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