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Article

Associative memory and in vivo brain pathology in asymptomatic presenilin-1 E280A carriers.

Neurology - 8 Sept 2020

Guzmán-Vélez Edmarie, Martínez Jairo, Papp Kate, Baena Ana, Vila-Castelar Clara, Artola Arabiye, Schultz Aaron P, Bocanegra Yamile, Sanchez Justin, Rentz Dorene, Tariot Pierre N, Reiman Eric M, Sperling Reisa, Johnson Keith A, Lopera Francisco, Quiroz Yakeel T

Abstract excerpt

OBJECTIVE: To determine whether performance on the Free and Cued Selective Reminding Test (FCSRT) is associated with PET in vivo markers of brain pathology and whether it can distinguish those who will develop dementia later in life due to autosomal-dominant Alzheimer disease (AD) from age-matched controls. METHODS: Twenty-four cognitively unimpaired Presenilin-1 E280A carriers (mean age 36 years) and 28...

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Identifiers

PMID: 32611637
DOI: 10.1212/WNL.0000000000010177
PMCID: PMC7538214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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