Article
Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease.
JAMA neurology - 1 May 2018
Quiroz Yakeel T, Sperling Reisa A, Norton Daniel J, Baena Ana, Arboleda-Velasquez Joseph F, Cosio Danielle, Schultz Aaron, Lapoint Molly, Guzman-Velez Edmarie, Miller John B, Kim Leo A, Chen Kewei, Tariot Pierre N, Lopera Francisco, Reiman Eric M, Johnson Keith A
Abstract excerpt
Importance: It is critically important to improve our ability to diagnose and track Alzheimer disease (AD) as early as possible. Individuals with autosomal dominant forms of AD can provide clues as to which and when biological changes are reliably present prior to the onset of clinical symptoms. Objective: To characterize the associations between amyloid and tau deposits in the brains of cognitively unimpaired...
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