Article
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease.
Neurology - 28 Aug 2012
Hu William T, Holtzman David M, Fagan Anne M, Shaw Leslie M, Perrin Richard, Arnold Steven E, Grossman Murray, Xiong Chengjie, Craig-Schapiro Rebecca, Clark Christopher M, Pickering Eve, Kuhn Max, Chen Yu, Van Deerlin Vivianna M, McCluskey Leo, Elman Lauren, Karlawish Jason, Chen-Plotkin Alice, Hurtig Howard I, Siderowf Andrew, Swenson Frank, Lee Virginia M-Y, Morris John C, Trojanowski John Q, Soares Holly
Abstract excerpt
OBJECTIVES: While plasma biomarkers have been proposed to aid in the clinical diagnosis of Alzheimer disease (AD), few biomarkers have been validated in independent patient cohorts. Here we aim to determine plasma biomarkers associated with AD in 2 independent cohorts and validate the findings in...
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