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Article

Constant compression decreases vascular bud and VEGFA expression in a rabbit vertebral endplate ex vivo culture model

25 Jun 2020

Abstract excerpt

SUMMARY OF BACKGROUND DATA: The vascular buds in the vertebral endplate (VEP) are the structural foundation of nutrient exchange in the intervertebral disc (IVD). VEGF is closely related to angiogenesis in the endplate and intervertebral disc degeneration (IDD). OBJECTIVE: To investigate the effects of static load on vascular buds and VEGF expression in the VEP and to further clarify the relation between IDD and...

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PMID: 32584845
DOI: 10.1371/journal.pone.0234747

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