Article
Interleukin-17 in Chronic Inflammatory Neurological Diseases.
Frontiers in immunology - 1 Jan 2020
Milovanovic Jelena, Arsenijevic Aleksandar, Stojanovic Bojana, Kanjevac Tatjana, Arsenijevic Dragana, Radosavljevic Gordana, Milovanovic Marija, Arsenijevic Nebojsa
Abstract excerpt
A critical role for IL-17, a cytokine produced by T helper 17 (Th17) cells, has been indicated in the pathogenesis of chronic inflammatory and autoimmune diseases. A positive effect of blockade of IL-17 secreted by autoreactive T cells has been shown in various inflammatory diseases. Several cytokines, whose production is affected by environmental factors, control Th17 differentiation and its maintenance in...
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