Article
Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer.
Journal of the National Cancer Institute - 1 Nov 2017
Morton Lindsay M, Sampson Joshua N, Armstrong Gregory T, Chen Ting-Huei, Hudson Melissa M, Karlins Eric, Dagnall Casey L, Li Shengchao Alfred, Wilson Carmen L, Srivastava Deo Kumar, Liu Wei, Kang Guolian, Oeffinger Kevin C, Henderson Tara O, Moskowitz Chaya S, Gibson Todd M, Merino Diana M, Wong Jeannette R, Hammond Sue, Neglia Joseph P, Turcotte Lucie M, Miller Jeremy, Bowen Laura, Wheeler William A, Leisenring Wendy M, Whitton John A, Burdette Laurie, Chung Charles, Hicks Belynda D, Jones Kristine, Machiela Mitchell J, Vogt Aurelie, Wang Zhaoming, Yeager Meredith, Neale Geoffrey, Lear Matthew, Strong Louise C, Yasui Yutaka, Stovall Marilyn, Weathers Rita E, Smith Susan A, Howell Rebecca, Davies Stella M, Radloff Gretchen A, Onel Kenan, Berrington de González Amy, Inskip Peter D, Rajaraman Preetha, Fraumeni Joseph F, Bhatia Smita, Chanock Stephen J, Tucker Margaret A, Robison Leslie L
Abstract excerpt
Background: Childhood cancer survivors treated with chest-directed radiotherapy have substantially elevated risk for developing breast cancer. Although genetic susceptibility to breast cancer in the general population is well studied, large-scale evaluation of breast cancer susceptibility after chest-directed radiotherapy for childhood cancer is lacking. Methods: We conducted a genome-wide association study of...
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