Article
Copy number and gene expression alterations in radiation-induced papillary thyroid carcinoma from chernobyl pediatric patients.
Thyroid : official journal of the American Thyroid Association - 1 May 2010
Stein Leighton, Rothschild Jenniffer, Luce Jesse, Cowell John K, Thomas Geraldine, Bogdanova Tatania I, Tronko Mycola D, Hawthorn Lesleyann
Abstract excerpt
BACKGROUND: Following exposure to radiation during the Chernobyl fallout tragedy, papillary thyroid carcinoma (PTC) increased significantly in individuals who were children at the time of the accident. We have used two high-throughput, whole genome platforms to analyze radiation-induced PTCs from pediatric patients from the Chernobyl region. METHODS: We performed comparative genomic hybridization using Affymetrix...
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