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Detection of de novo single nucleotide variants in offspring of atomic-bomb survivors close to the hypocenter by whole-genome sequencing.

Journal of human genetics - 1 Mar 2018

Horai Makiko, Mishima Hiroyuki, Hayashida Chisa, Kinoshita Akira, Nakane Yoshibumi, Matsuo Tatsuki, Tsuruda Kazuto, Yanagihara Katsunori, Sato Shinya, Imanishi Daisuke, Imaizumi Yoshitaka, Hata Tomoko, Miyazaki Yasushi, Yoshiura Koh-Ichiro

Abstract excerpt

Ionizing radiation released by the atomic bombs at Hiroshima and Nagasaki, Japan, in 1945 caused many long-term illnesses, including increased risks of malignancies such as leukemia and solid tumours. Radiation has demonstrated genetic effects in animal models, leading to concerns over the potential hereditary effects of atomic bomb-related radiation. However, no direct analyses of whole DNA have yet been...

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PMID: 29279608
DOI: 10.1038/s10038-017-0392-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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