Article
Allele-specific expression is widespread in Bos indicus muscle and affects meat quality candidate genes.
Scientific reports - 23 Jun 2020
de Souza Marcela Maria, Zerlotini Adhemar, Rocha Marina Ibelli Pereira, Bruscadin Jennifer Jessica, Diniz Wellison Jarles da Silva, Cardoso Tainã Figueiredo, Cesar Aline Silva Mello, Afonso Juliana, Andrade Bruno Gabriel Nascimento, Mudadu Mauricio de Alvarenga, Mokry Fabiana Barichello, Tizioto Polyana Cristine, de Oliveira Priscila Silva Neubern, Niciura Simone Cristina Méo, Coutinho Luiz Lehmann, Regitano Luciana Correia de Almeida
Abstract excerpt
Differences between the expression of the two alleles of a gene are known as allele-specific expression (ASE), a common event in the transcriptome of mammals. Despite ASE being a source of phenotypic variation, its occurrence and effects on genetic prediction of economically relevant traits are still unexplored in bovines. Furthermore, as ASE events are likely driven by cis-regulatory mutations, scanning them...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.