Article
Extensive variation between tissues in allele specific expression in an outbred mammal.
BMC genomics - 23 Nov 2015
Chamberlain Amanda J, Vander Jagt Christy J, Hayes Benjamin J, Khansefid Majid, Marett Leah C, Millen Catriona A, Nguyen Thuy T T, Goddard Michael E
Abstract excerpt
BACKGROUND: Allele specific gene expression (ASE), with the paternal allele more expressed than the maternal allele or vice versa, appears to be a common phenomenon in humans and mice. In other species the extent of ASE is unknown, and even in humans and mice there are several outstanding questions. These include; to what extent is ASE tissue specific? how often does the direction of allele expression imbalance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
