Article
Establishment of a pipeline to analyse non-synonymous SNPs in Bos taurus.
BMC genomics - 26 Nov 2006
Lee Michael A, Keane Orla M, Glass Belinda C, Manley Tim R, Cullen Neil G, Dodds Ken G, McCulloch Alan F, Morris Chris A, Schreiber Mark, Warren Jonathan, Zadissa Amonida, Wilson Theresa, McEwan John C
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) are an abundant form of genetic variation in the genome of every species and are useful for gene mapping and association studies. Of particular interest are non-synonymous SNPs, which may alter protein function and phenotype. We therefore examined bovine expressed sequences for non-synonymous SNPs and validated and tested selected SNPs for their association with...
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