Article
A comprehensive allele specific expression resource for the equine transcriptome.
BMC genomics - 30 Jan 2025
Heath Harrison D, Peng Sichong, Szmatola Tomasz, Ryan Stephanie, Bellone Rebecca R, Kalbfleisch Theodore, Petersen Jessica L, Finno Carrie J
Abstract excerpt
BACKGROUND: Allele-specific expression (ASE) analysis provides a nuanced view of cis-regulatory mechanisms affecting gene expression. RESULTS: An equine ASE analysis was performed, using integrated Iso-seq and short-read RNA sequencing data from four healthy Thoroughbreds (2 mares and 2 stallions) across 9 tissues from the Functional Annotation of Animal Genomes (FAANG) project. Allele expression was quantified...
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