Article
Morphological and functional abnormalities of hippocampus in APC1638T/1638T mice.
Medical molecular morphology - 1 Mar 2021
Li Chenguang, Onouchi Takanori, Hirayama Masaya, Sakai Kazuyoshi, Matsuda Shuji, Yamada Nami O, Senda Takao
Abstract excerpt
In the present study, we examined morphology and function of hippocampus in the APC1638T/1638T mouse. Expression levels of the APC mRNA and protein were both identical in the hippocampus of the APC+/+ and APC1638T/1638T mice. The dentate gyrus of the APC1638T/1638T hippocampus was thicker, and has more densely-populated granule cells in the APC1638T/1638T mouse hippocampus. Immunoelectron microscopy revealed...
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