Article
[A calcium-sensing receptor polymorphism at E942K promotes the proliferation of gastric cancer cells via Ca2+ and ERK1/2 pathways].
Sheng li xue bao : [Acta physiologica Sinica] - 25 Jun 2020
Zhang Ya-Bo, DU Chao, Lu Cheng, Dong Hui, Wu Xiao-Ling
Abstract excerpt
The study was designed to investigate the effects and mechanism of a calcium-sensing receptor (CaSR) polymorphism at E942K on the proliferation of gastric cancer cells. Single nucleotide polymorphisms (SNPs) were detected between gastric cancers group and normal controls group by DNA sequence analysis. The cell model was constructed by transfection of E942K mutant plasmid and wild-type (WT) plasmid into SGC-7901...
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