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Article

Genetic susceptibility on CagA-interacting molecules and gene-environment interaction with phytoestrogens: a putative risk factor for gastric cancer.

PloS one - 1 Jan 2012

Yang Jae Jeong, Cho Lisa Y, Ko Kwang-Pil, Shin Aesun, Ma Seung Hyun, Choi Bo Youl, Han Dong Soo, Song Kyu Sang, Kim Yong Sung, Lee Jong-Young, Han Bok Ghee, Chang Soung-Hoon, Shin Hai-Rim, Kang Daehee, Yoo Keun-Young, Park Sue K

Abstract excerpt

OBJECTIVES: To evaluate whether genes that encode CagA-interacting molecules (SRC, PTPN11, CRK, CRKL, CSK, c-MET and GRB2) are associated with gastric cancer risk and whether an interaction between these genes and phytoestrogens modify gastric cancer risk. METHODS: In the discovery phase, 137 candidate SNPs in seven genes were analyzed in 76 incident gastric cancer cases and 322 matched controls from the Korean...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Microscopy, Fluorescence

Share to Proto-Oncogene Proteins c-met

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Source

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Identifiers

PMID: 22383989
DOI: 10.1371/journal.pone.0031020
PMCID: PMC3286459

Genes

CRK
MET
SRC
CRKL
CSK
GRB2
PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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