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Article

ARID1A mutations and expression loss in non-small cell lung carcinomas: clinicopathologic and molecular analysis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2020

Hung Yin P, Redig Amanda, Hornick Jason L, Sholl Lynette M

Abstract excerpt

A subset of non-small cell lung carcinomas harbors mutations in ARID1A, a component of the SWI/SNF complex implicated in modulating response to immunotherapy in diverse tumors. This study characterized the spectrum of ARID1A mutations and expression by targeted sequencing and immunohistochemistry, respectively. In a consecutive series of 2440 non-small cell lung carcinomas, ARID1A mutations were present in 184...

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PMID: 32572156
DOI: 10.1038/s41379-020-0592-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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