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Article

Blood and saliva-derived exomes from healthy Caucasian subjects do not display overt evidence of somatic mosaicism.

Mutation research - 1 Jan 2000

Hall Nathan E, Mamrot Jared, Frampton Chris, Read Prue, Steele Edward J, Bischof Robert J, Lindley Robyn A

Abstract excerpt

Somatic mosaicism is a normal occurrence during development in the tissues and organs. As part of establishing a "healthy population "(HP) background or base-line, we investigated whether such mosaicism can be routinely detected in the circulating DNA secured from a rigorously designed healthy human liquid biopsy clinical trial (saliva, blood). We deployed next generation (NG) whole exome sequencing (WES) at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32569906
DOI: 10.1016/j.mrfmmm.2020.111705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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