Article
Mucinous borderline ovarian tumors with BRAFV600E mutation may have low risk for progression to invasive carcinomas.
Archives of gynecology and obstetrics - 1 Aug 2020
Ohnishi Kaori, Nakayama Kentaro, Ishikawa Masako, Ishibashi Tomoka, Yamashita Hitomi, Nakamura Kohei, Minamoto Toshiko, Iida Kouji, Razia Sultana, Ishikawa Noriyoshi, Kyo Satoru
Abstract excerpt
PURPOSE: Mucinous ovarian carcinomas (MOCs) are relatively rare. It has been proposed that a subset of mucinous cystadenomas (MCAs) may progress to mucinous borderline tumors (MBTs), and then to MOCs. KRAS is the predominantly mutated gene in MOC; however, other associated mutations and the mechanism underlying carcinogenesis in MOC remain unclear. Here, we assessed molecular genetic alterations in mucinous...
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