Article
Pre-invasive ovarian mucinous tumors are characterized by CDKN2A and RAS pathway aberrations.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2012
Hunter Sally M, Gorringe Kylie L, Christie Michael, Rowley Simone M, Bowtell David D, Campbell Ian G
Abstract excerpt
INTRODUCTION: Mucinous tumors are the second most common form of epithelial ovarian tumor, yet the cell of origin for this histologic subtype remains undetermined. Although these tumors are thought to arise through a stepwise progression from benign cystadenoma to borderline tumor to invasive carcinoma, few studies have attempted to comprehensively characterize the genetic changes specific to this subtype or its...
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