Article
Mucinous Cystic Neoplasms Lined by Abundant Mucinous Epithelium Frequently Involve KRAS Mutations and Malignant Progression.
Anticancer research - 1 Dec 2017
Shibata Hideki, Ohike Nobuyuki, Norose Tomoko, Isobe Tomohide, Suzuki Reika, Imai Hideyuki, Shiokawa Akira, Aoki Takeshi, Murakami Masahiko, Mizukami Hiroki, Tanaka Jun-Ichi, Takimoto Masafumi
Abstract excerpt
BACKGROUND: Pancreatic and hepatic mucinous cyst neoplasms (MCNs) have a malignant potential, but indolent MCNs are not uncommon. MATERIALS AND METHODS: The pathological and genetic characteristics of resected MCNs (n=15) categorized by the amount of mucin of the lining epithelium were investigated. RESULTS: MCNs were divided into two groups: (i) a rich (r)-MCN group (n=6), in which more than half of the...
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