Article
A new strategy to confirm the identity of tumour tissues using single-nucleotide polymorphisms and next-generation sequencing.
International journal of legal medicine - 1 Mar 2020
Sun Lijuan, Liu Qi, Li Shujin, Ma Guanju, Wang Zhandong, Ma Chunling, Cong Bin, Fu Lihong
Abstract excerpt
With growing cancer morbidity, forensics cases in which archived tumour tissues can be used as biological samples are increasing, and an effective method to identify the body source of tumour tissues is needed. Single nucleotide polymorphisms (SNPs) may be a promising biomarker to identify the source of tumour tissues because of their low mutation rate and small amplicon size. Next-generation sequencing...
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