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Article

Macrophage correlates with immunophenotype and predicts anti-PD-L1 response of urothelial cancer.

Theranostics - 1 Jan 2020

Zeng Dongqiang, Ye Zilan, Wu Jiani, Zhou Rui, Fan Xinxiang, Wang Gaofeng, Huang Yiqiang, Wu Jianhua, Sun Huiying, Wang Miaohong, Bin Jianping, Liao Yulin, Li Nailin, Shi Min, Liao Wangjun

Abstract excerpt

Immune-checkpoint blockades (ICBs) have been routinely implemented to treat metastatic urothelial cancer (mUC), whereas robust biomarkers are urgently warranted. Herein, we explored latent promising biomarkers based on 348 pretreatment mUC samples from IMvigor210. Methods: The genome, transcriptome, immunome, and metabolome were systemically analyzed using the external TCGA dataset for validation. Kaplan-Meier...

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Share to Antibodies, Monoclonal, Humanized
Share to Antineoplastic Agents, Immunological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to B7-H1 Antigen

Share to CD8-Positive T-Lymphocytes

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Source

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Identifiers

PMID: 32550918
DOI: 10.7150/thno.46176
PMCID: PMC7295060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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