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Clinical value of M1 macrophage-related genes identification in bladder urothelial carcinoma and in vitro validation

16 Nov 2022

Abstract excerpt

Background: Tumor microenvironment (TME) takes a non-negligible role in the progression and metastasis of bladder urothelial carcinoma (BLCA) and tumor development could be inhibited by macrophage M1 in TME. The role of macrophage M1-related genes in BLCA adjuvant therapy has not been studied well. Methods: CIBERSOR algorithm was applied for identification tumor-infiltrating immune cells (TICs) subtypes of...

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PMID: 36468020
DOI: 10.3389/fgene.2022.1047004

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