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Article

Identification of glucocorticoid receptor in Drosophila melanogaster.

BMC microbiology - 15 Jun 2020

Bartolo Gloria, Gonzalez Leandra O, Alameh Saleem, Valencia C Alexander, Martchenko Shilman Mikhail

Abstract excerpt

BACKGROUND: Vertebrate glucocorticoid receptor (GR) is an evolutionary-conserved cortisol-regulated nuclear receptor that controls key metabolic and developmental pathways. Upon binding to cortisol, GR acts as an immunosuppressive transcription factor. Drosophila melanogaster, a model organism to study innate immunity, can also be immunosuppressed by glucocorticoids. However, while the genome of fruit fly harbors...

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PMID: 32539689
DOI: 10.1186/s12866-020-01848-x
PMCID: PMC7296755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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