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Article

Endocrine-Disrupting Effects of Pesticides through Interference with Human Glucocorticoid Receptor

8 Dec 2015

Abstract excerpt

Many pesticides have been identified as endocrine-disrupting chemicals (EDCs) due to their ability to bind sex-steroid hormone receptors. However, little attention has been paid to the ability of pesticides to interfere with other steroid hormone receptors such as glucocorticoid receptor (GR) that plays a critical role in metabolic, endocrine, immune, and nervous systems. In this study, the glucocorticoidic and...

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PMID: 26647222
DOI: 10.1021/acs.est.5b03731

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