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The zoonotic pathogen Leptospira interrogans mitigates environmental stress through cyclic-di-GMP-controlled biofilm production.

NPJ biofilms and microbiomes - 12 Jun 2020

Thibeaux Roman, Soupé-Gilbert Marie-Estelle, Kainiu Malia, Girault Dominique, Bierque Emilie, Fernandes Julien, Bähre Heike, Douyère Anthony, Eskenazi Nicolas, Vinh Joëlle, Picardeau Mathieu, Goarant Cyrille

Abstract excerpt

The zoonotic bacterium Leptospira interrogans is the aetiological agent of leptospirosis, a re-emerging infectious disease that is a growing public health concern. Most human cases of leptospirosis result from environmental infection. Biofilm formation and its contribution to the persistence of virulent leptospires in the environment or in the host have scarcely been addressed. Here, we examined spatial and...

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Identifiers

PMID: 32532998
DOI: 10.1038/s41522-020-0134-1
PMCID: PMC7293261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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