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Functional crosstalk between T cells and monocytes in cancer and atherosclerosis

12 Jun 2020

Abstract excerpt

Monocytes and monocyte-derived cells, including Mϕs and dendritic cells, exhibit a diverse array of phenotypic states that are dictated by their surrounding microenvironment. These cells direct T cell activation and function via cues that range from being immunosuppressive to immunostimulatory. Solid tumors and atherosclerotic plaques represent two pathological niches with distinct immune microenvironments. While...

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PMID: 32531833
DOI: 10.1002/jlb.1mir0420-076r

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