Article
Diverse Hap43-independent functions of the Candida albicans CCAAT-binding complex.
Eukaryotic cell - 1 Jun 2013
Hsu Po-Chen, Chao Chun-Cheih, Yang Cheng-Yao, Ye Ya-Ling, Liu Fu-Chen, Chuang Yung-Jen, Lan Chung-Yu
Abstract excerpt
The CCAAT motif is ubiquitous in promoters of eukaryotic genomes. The CCAAT-binding complex (CBC) is conserved across a wide range of organisms, specifically recognizes the CCAAT motif, and modulates transcription directly or in cooperation with other transcription factors. In Candida albicans, CBC is known to interact with the repressor Hap43 to negatively regulate iron utilization genes in response to iron...
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