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Article

Function of glutaredoxin 3 (Grx3) in oxidative stress response caused by iron homeostasis disorder in Candida albicans.

Future microbiology - 1 Nov 2017

Zhang Dan, Dong Yijie, Yu Qilin, Kai Zhang, Zhang Meng, Jia Chang, Xiao Chenpeng, Zhang Bing, Zhang Biao, Li Mingchun

Abstract excerpt

AIM: Glutaredoxin is a conserved oxidoreductase in eukaryotes and prokaryotes. This study aimed to determine the role of Grx3 in cell survival, iron homeostasis and the oxidative stress response in Candida albicans. MATERIALS & METHODS: A grx3Δ/Δ mutant was obtained using PCR-mediated homologs recombination. The function of Grx3 was investigated by a series of biochemical methods. RESULTS: Deletion of GRX3...

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Source

Identifiers

PMID: 29039220
DOI: 10.2217/fmb-2017-0098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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