Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A circulating tumor cell-based digital assay for the detection of EGFR T790M mutation in advanced non-small cell lung cancer.

Journal of materials chemistry. B - 8 Jul 2020

Wang Jing, Sun Na, Lee Yi-Te, Ni Yiqian, Koochekpour Rose, Zhu Yazhen, Tseng Hsian-Rong, Wang Shuyang, Jiang Liyan, Zhu Hongguang

Abstract excerpt

Determining the status of epidermal growth factor receptor (EGFR) T790M mutation is crucial for guiding further treatment intervention in advanced non-small cell lung cancer (NSCLC) patients who develop acquired resistance to initial EGFR tyrosine kinase inhibitor (TKI) treatment. Circulating tumor cells (CTCs) which contain plentiful copies of well-preserved RNA offer an ideal source for noninvasive detection of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Nanostructures

Share to Nanotechnology

Share to Neoplastic Cells, Circulating

Share to Particle Size

Share to Surface Properties

Source

Open in PubMed Open full text

Identifiers

PMID: 32525199
DOI: 10.1039/d0tb00589d
PMCID: PMC8136811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A circulating tumor cell-based digital assay for the detection of EGFR T790M mutation in advanced non-small cell lung cancer.PMID 32525199Read ↗

Developing Ultrasensitive Library-Aliquot-Based Droplet Digital PCR for Detecting T790M in Plasma-Circulating Tumor DNA of Non-small-Cell-Lung-Cancer Patients.Semantic proximity Read ↗

Circulating tumor cells and DNA for real-time EGFR detection and monitoring of non-small-cell lung cancer.Semantic proximity Read ↗

Establishment and validation of a novel droplet digital PCR assay for ultrasensitive detection and dynamic monitoring of EGFR mutations in peripheral blood samples of non-small-cell lung cancer patients.Semantic proximity Read ↗

Optimal method for quantitative detection of plasma EGFR T790M mutation using droplet digital PCR system.Semantic proximity Read ↗

Dynamic Assessment of Tissue and Plasma EGFR-Activating and T790M Mutations with Droplet Digital PCR Assays for Monitoring Response and Resistance in Non-Small Cell Lung Cancers Treated with EGFR-TKIs.Semantic proximity Read ↗

Ultra-Sensitive Detection of the Pretreatment EGFR T790M Mutation in Non-Small Cell Lung Cancer Patients with an EGFR-Activating Mutation Using Droplet Digital PCR.Semantic proximity Read ↗

Evaluation of EGFR mutations in NSCLC with highly sensitive droplet digital PCR assaysSemantic proximity Read ↗

Up-front mutation detection in circulating tumor DNA by droplet digital PCR has added diagnostic value in lung cancerSemantic proximity Read ↗

Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNASemantic proximity Read ↗

Monitoring epidermal growth factor receptor C797S mutation in Japanese non-small cell lung cancer patients with serial cell-free DNA evaluation using digital droplet PCR.Semantic proximity Read ↗

Highly Sensitive Droplet Digital PCR Method for Detection of EGFR-Activating Mutations in Plasma Cell-Free DNA from Patients with Advanced Non-Small Cell Lung Cancer.Semantic proximity Read ↗

Droplet digital PCR improved the EGFR mutation diagnosis with pleural fluid samples in non-small-cell lung cancer patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.