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Article

Ex vivo study for the assessment of behavioral factor and gene polymorphisms in individual susceptibility to oxidative DNA damage metals-induced.

International journal of hygiene and environmental health - 1 Jun 2011

Di Pietro Angela, Baluce Barbara, Visalli Giuseppa, La Maestra Sebastiano, Micale Rosanna, Izzotti Alberto

Abstract excerpt

Transition metals in fine particulate matter generated by combustion induce oxidative DNA damage and inflammation. However, there is remarkable inter-individual variability in susceptibility to these damages. To assess this variability, an ex vivo study was performed using lymphocytes of 47 Caucasian healthy subjects. Cell samples were exposed to a water solution of oil fly ash (OFA). This was formed by the...

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Identifiers

PMID: 21334974
DOI: 10.1016/j.ijheh.2011.01.006

Genes

GSTT1
MTHFR
GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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