Article
Interplay between Clonal Hematopoiesis of Indeterminate Potential and Metabolism.
Trends in endocrinology and metabolism: TEM - 1 Jul 2020
Lee Man K S, Dragoljevic Dragana, Bertuzzo Veiga Camilla, Wang Nan, Yvan-Charvet Laurent, Murphy Andrew J
Abstract excerpt
Clonal hematopoiesis of indeterminate potential (CHIP), defined as a clone of hematopoietic cells consisting of a single acquired mutation during a lifetime, has recently been discovered to be a major risk factor for atherosclerotic cardiovascular disease (CVD). As such, this phenomenon has sparked interest into the role that these single mutations may play in CVD. Atherosclerotic CVD is a complex disease and we...
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