Article
The genetics of common kidney disease: a pathway toward clinical relevance.
Nature reviews. Nephrology - 28 Jun 2011
Drawz Paul E, Sedor John R
Abstract excerpt
Genome-wide association studies (GWASs) have advanced our understanding of the genetic basis for common renal diseases, including chronic kidney disease (CKD) and related traits such as hypertension. The 'common variant, common disease' hypothesis-the theoretical basis for gene mapping by GWASs-has, however, underestimated the complexity of the genetic architecture underlying these diseases. The disease-specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
