Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modelling neurodegenerative disease using brain organoids.

Seminars in cell & developmental biology - 1 Mar 2021

Wray Selina

Abstract excerpt

Neurodegenerative Diseases such as Alzheimer's Disease represent a major public health challenge, with no disease modifying therapies available. The availability of induced pluripotent stem cells from patients with phenotypes and genotypes of interest, that can be subsequently differentiated in vitro into disease-affected cell types, has revolutionised our ability to generate physiologically relevant disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Creutzfeldt-Jakob Syndrome
Share to Huntington Disease
Share to Induced Pluripotent Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neural Stem Cells

Share to Neuroglia

Share to Organ Specificity

Share to Organoids

Share to Tissue Culture Techniques

Source

Identifiers

PMID: 32513498
DOI: 10.1016/j.semcdb.2020.05.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modelling neurodegenerative disease using brain organoids.PMID 32513498Read ↗

Modeling neurological disorders using brain organoids.Semantic proximity Read ↗

Pushing the boundaries of brain organoids to study Alzheimer's disease.Semantic proximity Read ↗

Brain Organoids in Parkinson’s Disease Drug Development: Human-Specific Models for Translational DiscoverySemantic proximity Read ↗

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.Semantic proximity Read ↗

iPSCs and Organoids in Advancing Neuropathology Research and TherapiesSemantic proximity Read ↗

NEUBOrg: artificially induced pluripotent stem cell-derived brain organoid to model and study genetics of Alzheimer’s disease progression.Semantic proximity Read ↗

Brain organoids and insights on human evolutionSemantic proximity Read ↗

Brain Organoids: A Promising Living Biobank Resource for Neuroscience Research.Semantic proximity Read ↗

Aging phenotype in AD brain organoids: Track to success and challenges.Semantic proximity Read ↗

Organotypic brain slice cultures to model neurodegenerative proteinopathiesSemantic proximity Read ↗

Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 2: Spheroids, Organoids, and Disease ModelingSemantic proximity Read ↗

Differences between Cerebral Organoids Derived from a non-PD and a Parkinson’s Patient: A Potential Vulnerability for Neuroinvasive VirusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.