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IRESbase: A Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites

1 Apr 2020

Abstract excerpt

Internal ribosome entry sites (IRESs) are functional RNA elements that can directly recruit ribosomes to an internal position of the mRNA in a cap-independent manner to initiate translation. Recently, IRES elements have attracted much attention for their critical roles in various processes including translation initiation of a new type of RNA, circular RNA (circRNA), with no 5' cap to support classical...

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PMID: 32512182
DOI: 10.1016/j.gpb.2020.03.001

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