Article
C-Reactive Protein Promotes the Activation of Fibroblast-Like Synoviocytes From Patients With Rheumatoid Arthritis.
Frontiers in immunology - 1 Jan 2020
Fang Zhengyu, Lv Jiyang, Wang Jing, Qin Qingxia, He Juan, Wang Meiying, Zhou Gengmin, Liu Guoyu, Zhong Fubo, Zheng Yadan, Lan Hui-Yao, Wang Qingwen
Abstract excerpt
Objective: To evaluate the biological effect and mechanisms of C-reactive protein (CRP) on the activation of fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA). Study design: To understand if CRP is involved in RA, expression of CRP and its receptors CD32/64 was examined in synovial tissues from RA patients and normal controls. In vitro, the potential role and mechanisms of CRP in...
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