Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes.

Arthritis research & therapy - 1 Jan 2006

Bauer Stefan, Jendro Michael C, Wadle Andreas, Kleber Sascha, Stenner Frank, Dinser Robert, Reich Anja, Faccin Erica, Gödde Stefan, Dinges Harald, Müller-Ladner Ulf, Renner Christoph

Abstract excerpt

Fibroblast activation protein (FAP), as described so far, is a type II cell surface serine protease expressed by fibroblastic cells in areas of active tissue remodelling such as tumour stroma or healing wounds. We investigated the expression of FAP by fibroblast-like synoviocytes (FLSs) and compared the synovial expression pattern in rheumatoid arthritis (RA) and osteoarthritis (OA) patients. Synovial tissue from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endopeptidases
Share to Gelatinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyaluronan Receptors

Share to Matrix Metalloproteinase 1

Share to Matrix Metalloproteinase 13

Share to Myocytes, Smooth Muscle

Share to Osteoarthritis

Share to Synovial Membrane

Source

Open in PubMed Open full text

Identifiers

PMID: 17105646
DOI: 10.1186/ar2080
PMCID: PMC1794515

Genes

FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes.PMID 17105646Read ↗

Role of Fibroblast Activation Protein Alpha in Fibroblast-like Synoviocytes of Rheumatoid ArthritisSemantic proximity Read ↗

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis.Semantic proximity Read ↗

Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis.Semantic proximity Read ↗

Stable activation of fibroblasts in rheumatic arthritis-causes and consequences.Semantic proximity Read ↗

Distinct subsets of synovial fibroblasts control cartilage destruction in joint diseases.Semantic proximity Read ↗

Synovial fibroblasts: key players in rheumatoid arthritisSemantic proximity Read ↗

Fibroblast-like synoviocytes in rheumatoid arthritis: Surface markers and phenotypes.Semantic proximity Read ↗

Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis.Semantic proximity Read ↗

Inhibition of fibroblast activation protein partially restores the homeostatic phenotype of mechanoactivated synoviocytes.Semantic proximity Read ↗

Characterization of fibroblast-like synoviocytes from the synovial fluid of patients affected by juvenile idiopathic arthritis.Semantic proximity Read ↗

Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway.Semantic proximity Read ↗

Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.