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Article

Generation of human induced pluripotent stem cell (SKLRMi001-A) from a patient with partial androgen insensitivity syndrome (PAIS).

Stem cell research - 1 Jul 2020

Chen Junqing, Yang Xiaoyu, Fu Bifei, Zhu Pinmou, Zhu Yunfei, Guo Xuejiang, Sha Jiahao, Yuan Yan

Abstract excerpt

Androgen receptor (AR) is essential for maintaining normal spermatogenesis and male fertility, and its mutation can cause complete or partial androgen insensitivity syndrome (CAIS or PAIS) in patients. We established an induced pluripotent stem cell line (SKLRMi001-A) from a PAIS patient with AR mutation (c.2710G > A; p. V904M). The iPSC line expressed pluripotency markers, retained normal karyotype, carried the...

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Identifiers

PMID: 32505105
DOI: 10.1016/j.scr.2020.101863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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