Article
Induced pluripotent stem cell line from a mouse model of human azoospermia with a frameshift mutation Tex11_1260Ins(TT).
Stem cell research - 1 Apr 2022
Tran Kien T D, Sheng Yi, Doungkamchan Chatchanan, Castro Carlo A, Orwig Kyle E
Abstract excerpt
Infertility is a common disease that impacts 15% of reproductive age couples worldwide, and genetic causes are implicated in about half of those cases. Non-obstructive azoospermia is a severe form of male infertility that features spermatogenic failure resulting in no sperm in the ejaculate and severely reduces the chance to have biological children. We created a Tex11_1260Ins(TT) (1260GATA → TTGGTA) mutant mouse...
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