Article
Generation of a human induced pluripotent stem cell line (WMUi021-A) from a Gitelman syndrome patient carrying a SLC12A3 gene mutation (c.179C > T).
Stem cell research - 1 May 2021
Guo Xiaoling, Qian Rengchen, Shan Xiaoou, Yang Liang, Chen Huihui, Ding Yinjuan, Chen Congde, Chu Maoping, Lin Jian, Wang Dexuan
Abstract excerpt
Gitelman Syndrome (GS) is an inherited autosome recessive disorder syndrome, which can be caused by the gene mutations of solute carrier family 12 member 3 gene (SLC12A3). In present study, the urine cells (UCs) of a 7-year-old male GS patient with the homozygote SLC12A3 gene mutation p.T60M (c.179C > T) were reprogrammed into induced pluripotent stem cells (iPSCs) named WMUi021-A through the commercial Sendai...
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